Used to determine effectiveness of new drug candidates, typically conducted in a high-throughput manner.
Assess safety and efficacy of new drugs. Studies effects on specific tissues/cells (isolated organs/cultures) or whole organism (animal models).
Non-specific tests gathering information about drug effects. Includes observations of animal behavior, physiology, or anatomy.
Confirmatory tests confirm findings of earlier studies. Analogous activities are similar but not for regulatory purposes.
Determines drug safety, typically conducted in a dose-dependent manner to see effects at different doses.
Studies the biochemical process by which a drug produces its effect.
Studies the effects of a drug on the whole body.
Measures drug effects. Can measure drug concentration, amount metabolized, or effects on specific organs.
Studies how the body absorbs, distributes, metabolizes, and excretes a drug.
Tests the compatibility of a medical device with living tissue.
Ensures that a medical device is free from microorganisms.
Ensures that a medical device is properly packaged to maintain sterility.
Breed animals with specific genetic modifications for research purposes.
Develop custom strains of animals to meet specific research needs.
Provide animal care and husbandry services for research animals.
Tests the toxic effects of a single exposure to a substance.
Tests the toxic effects of repeated exposure to a substance over a short period.
Tests the toxic effects of repeated exposure to a substance over a long period.